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a16z crypto outlines top 5 trends shaping crypto’s future in 2025

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From mobile wallets to transaction fees, a16z crypto breaks down the top indicators shaping the crypto landscape in 2025.

The year 2024 was transformative for the crypto space as activity reached all-time highs, transaction fees dropped, stablecoins found practical use cases, and spot Bitcoin (BTC) and Ethereum (ETH) exchange-traded funds finally received approval. Meanwhile, regulatory clarity began to emerge, offering the sector a more defined path forward. As 2025 begins, here are five metrics a16z’s partner Daren Matsuoka believes worth monitoring.

Mobile crypto wallets

Crypto wallets on mobile are where the action is. In 2024, over 35 million people were using them monthly, Matsuoka notes, bringing up such big names as Coinbase Wallet, MetaMask, and Trust Wallet, who are leading the charge. At the same time, newer apps like Solana-focused Phantom and World App are gaining steam too.

Mobile crypto applications have grown so popular that they now serve as an informal indicator of retail investor interest, with observers identifying a correlation between their high rankings in Apple’s App Store and rising crypto prices.

While millions own crypto, many remain passive holders. For broader adoption, Matsuoka says blockchain developers need to find the “right balance between security, privacy, and usability,” admitting that the task is “not trivial.” Nonetheless, the a16z partner believes blockchain infrastructure can now handle “hundreds of millions — or billions — of people on-chain,” adding it’s a “better time than ever to build a next-generation mobile wallet” than ever before.

According to data from Statista, the countries with the highest mobile wallet adoption are in Asia, despite the presence of major U.S. brands like PayPal, Apple Pay, and Google Pay. This trend is not accidental given that in emerging markets, mobile wallets are being used as a tool to address the issue of unbanked populations. As a result, the next major innovation in mobile crypto wallets may well emerge from this region.

Stablecoins everywhere

Stablecoins had a big moment in 2024. Lower transaction fees made them even more useful for stuff like cross-border payments, remittances, and even just buying everyday stuff. They’re also helping people in countries with crazy inflation store value (e.g. Argentina and Turkey).

“Stablecoins are already the cheapest way to send a dollar, and we expect enterprises will increasingly accept stablecoins for payments.”

Daren Matsuoka

Yet, there’s still no dominant solution that brings stablecoin payments closer to traditional methods, leaving a significant gap in the market.

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Monthly active unique stablecoin wallets | Source: Visa

Matsuoka notes that stablecoin payments are quickly gaining traction and show no signs of slowing down as payment giant Visa has developed a dashboard to distinguish genuine stablecoin usage from bot-driven transactions.

“If stablecoin adoption — one of crypto’s most clear use cases — takes off in 2025, this metric will be one to watch,” says Matsuoka.

ETPs bring Bitcoin and Ethereum to masses

Last year, Bitcoin and Ethereum got their first proper exchange-traded funds approved in the U.S. This makes it way easier for regular people — and big institutions — to invest in crypto.

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Bitcoin ETF flows | Source: Dune

However, so far these ETFs have attracted only 515,000 BTC (around $110 billion) and 611,000 ETH (~$13 billion), Matsuoka notes, adding that “activating the distributors – the likes of Goldman Sachs, JP Morgan, and Merrill Lynch, who can get these products into retail investors’ portfolios – is going to take time.”

The a16z partner suggests tracking on-chain deposits and withdrawals of addresses “identified as custodians of the ETPs,” noting that more institutional investors are likely to seek exposure to crypto assets, which will lead to increased net flows for the ETPs.

DEXs vs CEXs

Decentralized exchanges are slowly eating into centralized exchanges’ market share. While their trading volume is still far from centralized rivals, they already handle about 11% of spot trading, Matsuoka pointed out, adding that the number’s climbing.

“Recently, DEX volume hit an all-time high — driven by a major uptick in transaction volume on high-throughput chains like Coinbase’s Base and Solana as new users entered the space.”

Daren Matsuoka

Although Matsuoka says DEXs are likely to keep gaining their share in 2025, it’s unclear whether retail investors will rush to switch from centralized platforms. So far, the pace has been slow, as it took decentralized trading platforms four years to capture more than 10% of spot trading volume compared to their centralized counterparts, per data from DefiLlama.

Transaction fees

In a bid to identify which blockchain network is gaining in popularity, transaction fees could show how much demand there is. But here’s the catch: while fees should show growth, they shouldn’t go so high they scare users away.

Last year, Solana passed Ethereum in total fees collected for the first time, even though Solana’s transactions are extremely cheap (less than 1 cent vs. $5+ on Ethereum). Matsuoka admits that that’s a big milestone, adding that many ecosystems and their associated fee markets are maturing, making it a “good time to start measuring the economic value facilitated by various blockchains.”

In the long run, demand for blockspace – measured as the total aggregate USD value of fees paid – could be the most important metric for tracking the crypto industry’s progress, as it reflects engagement in valuable economic activities and users’ willingness to pay for them, Matsuoka wrote.



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Will a16z Crypto Policy Lead Brian Quintenz be the new US CFTC Chair?

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As the Donald Trump administration looks to appoint the US Commodity Futures Trading Commission (CFTC) chairman, a16z Crypto policy lead Brian Quintenz emerged as the top contender. According to sources familiar with the matter, the Trump team has recently interviewed Quintenz for the top job at US CFTC.

Brian Quintenz Is the Top Choice for US CFTC Chair

As per a Bloomberg report, former Republican CFTC Commissioner Brian Quintenz was interviewed for the top position in the regulatory body. He is currently leading the crypto policy division at the digital asset wing of VC giant Andreessen Horowitz, a16z Crypto.

President-elect Donald Trump’s team has been actively conducting interviews for the US CFTC chair position, with an announcement likely in the coming days. Republican CFTC Commissioners Summer Mersinger and Caroline Pham have also been in the race for the same. Last month, reports suggested that Crypto Dad Chris Giancarlo could be the top boss at CFTC, however, he dispelled the rumors.

If chosen to lead CFTC, Brian Quintenz could bring a new perspective that bridges traditional finance (TradFi) and digital assets. During his previous tenure as CFTC Commissioner under the Donald Trump administration, Quintenz advocated for the agency to embrace innovative financial services, that included crypto derivatives and event contracts. In a crypto blog last month, co-authored with a16z, Quintenz shared his perspective on the election’s implications for the future of crypto. He wrote:

“While we’ll likely have greater flexibility to experiment, we can’t forget that the fundamental regulatory principles applicable to blockchain systems remain unchanged. There will still be valid scrutiny from regulators and policymakers of certain aspects of the industry irrespective of progress on new legislation or a re-calibrated regulatory environment”.

Since joining venture capital firm Andreessen Horowitz (a16z), Quintenz has continued championing progressive regulatory approaches for these industries. Quintenz’s extensive experience positions him to navigate the agency through significant policy changes under the Biden administration.

Furthermore, recent reports suggest that the Donald Trump administration is considering giving US CFTC the oversight of the $3 trillion crypto market. The proposal focuses on digital assets like Bitcoin and Ethereum, classified as commodities under current law. If implemented, it would grant the CFTC authority to oversee spot markets and exchanges.

US Crypto Policy to Undergo Key Changes

Crypto market analysts hope for a major US crypto policy shift under the Trump administration, with Brian Quintenz as CFTC Chair expected to play a key role. The appointment of pro-crypto Paul Atkins as the next US SEC chair already hints at this possibility and a conducive environment for crypto innovation.

The crypto industry has been demanding clarity on crypto policy from the US Congress and regulators on which products and services fall under the jurisdiction of the US CFTC or the US SEC. During his election campaign, Donald Trump pledged to make America the Crypto Capital of the world.

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Bhushan Akolkar

Bhushan is a FinTech enthusiast with a keen understanding of financial markets. His interest in economics and finance has led him to focus on emerging Blockchain technology and cryptocurrency markets. He is committed to continuous learning and stays motivated by sharing the knowledge he acquires. In his free time, Bhushan enjoys reading thriller fiction novels and occasionally explores his culinary skills.

Disclaimer: The presented content may include the personal opinion of the author and is subject to market condition. Do your market research before investing in cryptocurrencies. The author or the publication does not hold any responsibility for your personal financial loss.





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DeFi remains popular amid explosion in crypto usage: a16z report

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The decentralized finance ecosystem continues to grow despite recent challenges as overall crypto usage hits record levels, venture capital firm Andreessen Horowitz (a16z) said in a new report.

In its “State of Crypto” report published on Oct. 16, a16z noted that the crypto industry has witnessed a major spike in activity over the past year. The growth trajectory for the industry is “reminiscent of early internet adoption.”

For instance, September 2024 saw 220 million addresses interact with protocols across the blockchain ecosystem—more than triple the figures recorded in late 2023. About 100 million of these active addresses were on Solana (SOL), a blockchain network that has registered a massive spike in activity.

As well as Solana, other networks to see a significant increase in active addresses are Near Protocol (NEAR), Coinbase’s layer-2 network Base, Tron (TRX) and Bitcoin (BTC).

Stablecoin and crypto regulation

The report also highlighted several growth metrics and key issues surrounding the crypto industry since a16z’s first State of Crypto report in 2023.

One major takeaway is that crypto has become a significant political issue amid the U.S. election. However, the United States lags behind the European Union and the United Kingdom in public engagement regarding crypto regulation.

The market has also seen considerable developments around stablecoins, including their regulation and usage. Notably, stablecoins have grown to become one of the top 20 holders of U.S. Treasury securities, with a Coinbase report showing marked growth in Q3, 2024. Major players include Tether’s USDT and Circle’s USDC.

Additionally, infrastructure improvements and the increasing intersection of blockchain technology and artificial intelligence have further bolstered the industry’s growth.

DeFi continues to grow

DeFi has been one of the areas of crypto that saw the most usage across daily active addresses in the past year.

“Since DeFi’s arrival in the summer of 2020, decentralized exchanges, or DEXs, have grown to account for 10% of spot crypto trading activity — all of which occurred on centralized exchanges just four years ago,” the reports reads.

DeFi protocols across the ecosystem now account for over $169 billion in total value locked. Top platforms include Lido, Aave, Uniswap, EigenLayer, WBTC, and ether.fi. These decentralized platforms continue to attract users as traditional financial institutions, such as U.S. banks, face ongoing challenges.

According to a16z, top blockchains in terms of builder activity or interest include Ethereum (ETH), Solana and Bitcoin.

While Ethereum still attracts the most developer activity, with 20.8% of builders, Solana has seen significant growth in this sector, increasing from 5.1% in 2023 to 11.2% in 2024.

Base also recorded a notable jump in developer activity, rising from 7.8% to 10.7% year-over-year. Bitcoin, which has registered a surge in DeFi-related activity, saw an increase in builder interest from 2.6% to 4.2%.



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